On December 9, the research findings of the team led by Zhang Heping from Inner Mongolia Agricultural University in collaboration with the team of Director Zhu Cuifeng from the Clinical Nutrition Department of Shenzhen Hospital, Southern Medical University, were published in the journal Gut Microbes. The study included 45 healthy children and 53 children with autism spectrum disorder (ASD). It was found that the abundances of Prevotella and Bacteroides in the gut microbiota of children with ASD significantly decreased. After a 3 - month intervention with probiotic Probio - M8 combined with a medium - carbohydrate diet in 53 children with ASD, the CARS and GSRS scores of the children were significantly improved. The abundances of Bifidobacterium animalis and Akkermansia muciniphila in feces increased, and the abundance of Blautia decreased. The enteric microbial metabolites related to amino acid, neurotransmitter, polyunsaturated fatty acid and vitamin B3 metabolism were significantly regulated, thus improving the severity of clinical symptoms through the two - way communication of the gut - brain axis.